This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Contents
Part I Introduction
1. General Features of the Cardiovascular System

Part II Anatomy
Attitudinally Correct Cardiac Anatomy
3. Cardiac Development
4. Anatomy of the Thoracic Wall, Pulmonary Cavities, and Mediastinum
5. Anatomy of the Human Heart
6. Comparative Cardiac Anatomy
7. Detailed Anatomical and Functional Features of the Cardiac Valves
8. The Coronary Vascular System and Associated Medical Devices
9. The Pericardium
10. Congenital Cardiac Anatomy and Operative Correction
11. Mechanical Circulatory Support Devices in Pediatric Patients

Part III Physiology and Assessment
12. Cellular Myocytes
13. The Cardiac Conduction System
14. Autonomic Nervous System
15. Cardiac and Vascular Receptors and Signal Transduction
16. Reversible and Irreversible Damage of the Myocardium: Ischemia/Reperfusion Injury and Cardioprotection
17. The Effects of Anesthetic Agents on Cardiac Function
18. Blood Pressure, Heart Tones, and Diagnoses
19. Basic ECG Theory, 12-Lead Recordings, and Their Interpretation
20. Mechanical Aspects of Cardiac Performance
21. Fueling Normal and Diseased Hearts: Myocardial Bioenergetics
22. Introduction to Echocardiography
23. Monitoring and Managing the Critically Ill Patient in the Intensive Care Unit
24. Cardiovascular Magnetic Resonance Imaging and MR-Conditional Cardiac Devices

Part IV Devices and Therapies
25. Historical Perspective of Cardiovascular Devices and Techniques Associated with the University of Minnesota
26. Pharmacotherapy for Cardiac Diseases
27. Animal Models for Cardiac Research
28. Catheter Ablation of Cardiac Arrhythmias
29. Cardiac Ablative Technologies
30. Pacing and Defibrillation
31. Cardiac Resynchronization Therapy
32. Cardiac Mapping Technology
33. Cardiopulmonary Bypass and Cardioplegia
34. Heart Valve Disease
35. Less Invasive Cardiac Surgery
36. Transcatheter Valve Repair and Replacement
37. Cardiac Septal Defects: Treatment via the Amplatzer® Family of Devices
38. Harnessing Cardiopulmonary Interactions to Improve Circulation and Outcomes After Cardiac Arrest and Other States of Low Blood Pressure
39. End-Stage Congestive Heart Failure in the Adult Population: Ventricular Assist Devices
40. Cell Transplantation for Ischemic Heart Disease
41. The Use of Isolated Heart Models and Anatomical Specimens as Means to Enhance the Design and Testing of Cardiac Devices
42. Current Status of Development and Regulatory Approval of Cardiac Devices
43. Clinical Trial Requirements for Cardiac Devices
44. Cardiac Devices and Technologies: Continued Rapid Rates of Development